No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
6142 |
4. Check minimum number of eventsNone |
6142 |
5. Include endpointsNone |
6142 |
6. Filter based on genotype QC (FinnGen only) |
5945 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D12
Name in latin
Neoplasma benignum recti
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Rectum
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Rectum
- Benign neoplasm: Rectum, anus and anal canal
- Benign neoplasm: Rectum, anus and anal canal
- Benign neoplasm of colon, rectum, anus and anal canal
- Benign neoplasm of colon, rectum, anus and anal canal
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 36424 | 17899 | 18367 |
| Only index persons | 34257 | 17060 | 17197 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.51 | 0.51 | 0.51 |
| Only index persons | 0.64 | 0.63 | 0.66 |
| Median age at first event (years) | |||
| Whole population | 66.72 | 66.83 | 66.59 |
| Only index persons | 66.35 | 66.46 | 66.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 5945 | 2807 | 3138 |
| Unadjusted period prevalence (%) | 1.35 | 1.10 | 1.58 |
| Median age at first event (years) | 65.95 | 64.39 | 67.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_RECTUM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_RECTUM | 1.154 [1.05, 1.26] | 0.002 |
| Birth year | 0.994 [0.99, 1.0] | 0.162 |
During the follow-up period (1.1.1998 — 31.12.2019), 3166 out of 15053 females with CD2_BENIGN_RECTUM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_RECTUM | 1.235 [1.13, 1.35] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 4227 out of 15319 males with CD2_BENIGN_RECTUM died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_RECTUM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.093% | 0.236% |
| 5 | 0.562% | 1.354% |
| 10 | 1.649% | 3.303% |
| 15 | 3.229% | 6.434% |
| 20 | 5.829% | 11.181% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_RECTUM – Benign neoplasm: Rectum
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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