biliary tract neoplasm: A neoplasm that involves the biliary tract.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
765 |
6. Filter based on genotype QC (FinnGen only) |
744 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Liver/bile ducts
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Liver/bile ducts
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4652 | 3169 | 1446 |
| Only index persons | 4204 | 2945 | 1259 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.09 | 0.04 |
| Only index persons | 0.09 | 0.11 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 53.05 | 49.88 | 59.76 |
| Only index persons | 51.67 | 48.81 | 58.37 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 744 | 526 | 218 |
| Unadjusted period prevalence (%) | 0.18 | 0.21 | 0.11 |
| Median age at first event (years) | 53.47 | 49.44 | 63.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_LIVE_BILE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LIVE_BILE | 1.65 [1.41, 1.93] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.164 |
During the follow-up period (1.1.1998 — 31.12.2019), 315 out of 2402 females with CD2_BENIGN_LIVE_BILE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LIVE_BILE | 1.985 [1.62, 2.42] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1102 males with CD2_BENIGN_LIVE_BILE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_LIVE_BILE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.15% | 0.324% |
| 5 | 0.89% | 2.124% |
| 10 | 2.35% | 5.521% |
| 15 | 4.438% | 10.241% |
| 20 | 7.635% | 16.824% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_LIVE_BILE – Benign neoplasm: Liver/bile ducts
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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