common bile duct neoplasm: Tumor or cancer of the common bile duct including the ampulla of vater and the sphincter of oddi.
Benign neoplasm: Extrahepatic bile ducts
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_EXTRAHEPATIC_BILE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
90 |
4. Check minimum number of eventsNone |
90 |
5. Include endpointsNone |
90 |
6. Filter based on genotype QC (FinnGen only) |
88 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum ductuum biliarium extrahepaticorum
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Extrahepatic bile ducts
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Extrahepatic bile ducts
- Benign neoplasm: Liver/bile ducts
- Benign neoplasm: Liver/bile ducts
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 741 | 435 | 299 |
| Only index persons | 639 | 388 | 251 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 60.15 | 58.14 | 63.18 |
| Only index persons | 59.14 | 57.39 | 61.84 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 88 | 47 | 41 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 60.18 | 53.97 | 67.30 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_EXTRAHEPATIC_BILE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EXTRAHEPATIC_BILE | 1.636 [1.22, 2.19] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.484 |
During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 312 females with CD2_BENIGN_EXTRAHEPATIC_BILE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EXTRAHEPATIC_BILE | 1.638 [1.19, 2.25] | 0.002 |
| Birth year | 0.989 [0.98, 1.0] | 0.018 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 232 males with CD2_BENIGN_EXTRAHEPATIC_BILE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_EXTRAHEPATIC_BILE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.216% | 0.35% |
| 5 | 1.007% | 2.019% |
| 10 | 2.387% | 5.015% |
| 15 | 4.663% | 9.497% |
| 20 | 8.047% | 15.926% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_EXTRAHEPATIC_BILE – Benign neoplasm: Extrahepatic bile ducts
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data