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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_COLON_ADENO_EXALLC for full statistics.

Colon adenocarcinoma

DOID Endpoint Browser

C3_COLON_ADENO

colon adenocarcinoma: An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • HLP_C3_COLON_ADENO
4303

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C18
  • Cause of death: ICD-9 — 153
  • Cause of death: ICD-8 — 153
  • Cancer registry: Topography ICD-O-3 — C18
  • Cancer registry: Morphology ICD-O-3 — 8140
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

4303

4. Check minimum number of events

None

4303

5. Include endpoints

4303

6. Filter based on genotype QC (FinnGen only)

4147

Control definitions (FinnGen only)

Control conditions not HLP_C3_COLON_ADENO

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF8

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 4147 1773 2374
Unadjusted period prevalence (%) 0.98 0.70 1.19
Median age at first event (years) 70.09 69.15 70.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_COLON_ADENO – Colon adenocarcinoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).