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Malignant neoplasm of breast, HER2-negative

Endpoint Browser

C3_BREAST_HER2NEG_EXALLC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only females

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2. Check conditions

  • not RX_HER2PLUS
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3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C50
  • Cause of death: ICD-9 — 174
  • Cause of death: ICD-8 — 174
  • Cancer registry: Topography ICD-O-3 — C50
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — ANY

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE
Control conditions not RX_HER2PLUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 20550 20550 -
Unadjusted period prevalence (%) 8.07 8.07 -
Median age at first event (years) 59.37 59.37 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_BREAST_HER2NEG_EXALLC – Malignant neoplasm of breast, HER2-negative

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).