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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_BREAST_HER2NEG_EXALLC for full statistics.

Malignant neoplasm of breast, HER2-negative

Endpoint Browser

C3_BREAST_HER2NEG

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

-

2. Check conditions

  • not RX_HER2PLUS
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C50
  • Cause of death: ICD-9 — 174
  • Cause of death: ICD-8 — 174
  • Cancer registry: Topography ICD-O-3 — C50
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — ANY

2 out of 7 registries used, show all original rules.

21213

4. Check minimum number of events

None

21213

5. Include endpoints

None

21213

6. Filter based on genotype QC (FinnGen only)

20550

Control definitions (FinnGen only)

Control conditions not RX_HER2PLUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 20550 20550 -
Unadjusted period prevalence (%) 8.07 8.07 -
Median age at first event (years) 59.37 59.37 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_BREAST_HER2NEG – Malignant neoplasm of breast, HER2-negative

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).