No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3020 |
4. Check minimum number of eventsNone |
3020 |
5. Include endpointsNone |
3020 |
6. Filter based on genotype QC (FinnGen only) |
2940 |
Control definitions (FinnGen only)
Control exclude
F5_DEMENTIA, G6_ALZHEIMER, G6_AD_WIDE
Extra metadata
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G45
Name in latin
Amnesia globalis transitoria
Similar endpoints
↥List of similar endpoints to
Transient global amnesia
based on the number of shared cases.
Similar with more cases:
- Episodal and paroxysmal disorders
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 22018 | 13919 | 8054 |
| Only index persons | 21181 | 13464 | 7717 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.33 | 0.40 | 0.23 |
| Only index persons | 0.42 | 0.49 | 0.29 |
| Median age at first event (years) | |||
| Whole population | 65.05 | 65.94 | 63.49 |
| Only index persons | 64.81 | 65.69 | 63.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2940 | 1823 | 1117 |
| Unadjusted period prevalence (%) | 0.66 | 0.72 | 0.56 |
| Median age at first event (years) | 64.34 | 64.45 | 64.17 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint AMN2 and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AMN2 | 0.684 [0.62, 0.75] | < 0.001 |
| Birth year | 0.993 [0.99, 1.0] | 0.118 |
During the follow-up period (1.1.1998 — 31.12.2019), 1666 out of 12153 females with AMN2 died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AMN2 | 0.671 [0.61, 0.74] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 1155 out of 7074 males with AMN2 died.
Mortality risk
Mortality risk for people of age
years, who have AMN2.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.076% | 0.124% |
| 5 | 0.402% | 0.704% |
| 10 | 0.974% | 1.922% |
| 15 | 1.879% | 3.694% |
| 20 | 3.266% | 6.373% |
Relationships between endpoints
↥Index endpoint: AMN2 – Transient global amnesia
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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