This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Tuberculosis of nervous system
AB1_TUBERCU_NEU
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
45 |
4. Check minimum number of eventsNone |
45 |
5. Include endpointsNone |
45 |
6. Filter based on genotype QC (FinnGen only) |
41 |
Control definitions (FinnGen only)
Control exclude
AB1_TUBERCULOSIS
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Tuberculosis of nervous system
based on the number of shared cases.
Similar with more cases:
- Tuberculosis of nervous system
- Tuberculosis, IBD comorbidity
- Tuberculosis
- Infections, IBD-co-morbidities
- Certain infectious and parasitic diseases
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 600 | 293 | 286 |
| Only index persons | 340 | 181 | 159 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 58.42 | 59.18 | 58.14 |
| Only index persons | 50.32 | 47.69 | 53.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 41 | 21 | 20 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 52.53 | 42.48 | 63.08 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint AB1_TUBERCU_NEU and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_TUBERCU_NEU | 3.102 [1.98, 4.86] | < 0.001 |
| Birth year | 0.985 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 121 males with AB1_TUBERCU_NEU died.
Mortality risk
Mortality risk for people of age
years, who have AB1_TUBERCU_NEU.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.547% |
| 5 | No data | 3.433% |
| 10 | No data | 8.635% |
| 15 | No data | 15.568% |
| 20 | No data | 24.871% |
Relationships between endpoints
↥Index endpoint: AB1_TUBERCU_NEU – Tuberculosis of nervous system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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