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Pediculosis, acariasis and other infestations

DOID EFO Endpoint Browser PheWeb

AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B85-B89
  • Hospital discharge: ICD-9 — 13[2-4]
  • Hospital discharge: ICD-8 — 13[2-4]
  • Cause of death: ICD-10 — B85-B89
  • Cause of death: ICD-9 — 13[2-4]
  • Cause of death: ICD-8 — 13[2-4]

2 out of 7 registries used, show all original rules.

1767

4. Check minimum number of events

None

1767

5. Include endpoints

2030

6. Filter based on genotype QC (FinnGen only)

1964

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 25111 8819 16113
Only index persons 21263 7492 13771
Unadjusted period prevalence (%)
Whole population 0.38 0.25 0.45
Only index persons 0.44 0.28 0.53
Median age at first event (years)
Whole population 21.80 23.25 20.75
Only index persons 21.54 23.12 20.67

-FinnGen-

Key figures

All Female Male
Number of individuals 1964 831 1133
Unadjusted period prevalence (%) 0.47 0.33 0.57
Median age at first event (years) 24.59 27.54 22.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST and mortality.

Females

Parameter HR [95% CI] p-value
AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST 1.758 [1.47, 2.11] < 0.001
Birth year 0.994 [0.99, 1.0] 0.179

During the follow-up period (1.1.1998 — 31.12.2019), 525 out of 4530 females with AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST died.

Males

Parameter HR [95% CI] p-value
AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST 2.101 [1.76, 2.5] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 744 out of 5914 males with AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST died.

Mortality risk

Mortality risk for people of age

years, who have AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST.

N-year risk Females Males
1 0.139% 0.388%
5 0.834% 2.288%
10 2.453% 5.89%
15 4.616% 10.678%
20 8.25% 17.124%

Relationships between endpoints

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Index endpoint: AB1_PEDICULOSIS_ACARIASIS_OTHERINFEST – Pediculosis, acariasis and other infestations

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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