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Pediculosis and phthiriasis

Endpoint Browser PheWeb

AB1_PEDICULOSIS_AND_PHTHIRIAASIS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B85
  • Hospital discharge: ICD-9 — 13[2-3]
  • Hospital discharge: ICD-8 — 13[2-3]
  • Hospital discharge: excluded ICD-9 — 1330A
  • Hospital discharge: excluded ICD-8 — 13[3-4]0
  • Cause of death: ICD-10 — B85
  • Cause of death: ICD-9 — 13[2-3]
  • Cause of death: ICD-8 — 13[2-3]
  • Cause of death: excluded ICD-9 — 1330A
  • Cause of death: excluded ICD-8 — 13[3-4]0

2 out of 7 registries used, show all original rules.

110

4. Check minimum number of events

None

110

5. Include endpoints

None

110

6. Filter based on genotype QC (FinnGen only)

105

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1345 425 908
Only index persons 1108 349 759
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.03
Only index persons 0.02 0.01 0.03
Median age at first event (years)
Whole population 22.48 24.94 20.92
Only index persons 22.02 24.94 20.68

-FinnGen-

Key figures

All Female Male
Number of individuals 105 30 75
Unadjusted period prevalence (%) 0.03 0.01 0.04
Median age at first event (years) 23.97 29.07 21.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

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Association

Association between endpoint AB1_PEDICULOSIS_AND_PHTHIRIAASIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
AB1_PEDICULOSIS_AND_PHTHIRIAASIS 3.346 [2.54, 4.41] < 0.001
Birth year 0.988 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 328 males with AB1_PEDICULOSIS_AND_PHTHIRIAASIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_PEDICULOSIS_AND_PHTHIRIAASIS.

N-year risk Females Males
1 No data 0.722%
5 No data 4.328%
10 No data 10.4%
15 No data 18.78%
20 No data 30.318%

Relationships between endpoints

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Index endpoint: AB1_PEDICULOSIS_AND_PHTHIRIAASIS – Pediculosis and phthiriasis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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