No definition available.
Suicide or other Intentional self-harm
EFO MESH Endpoint Browser PheWeb
VWXY20_SUICI_OTHER_INTENTI_SELF_H
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
10997 |
4. Check minimum number of eventsNone |
10997 |
5. Include endpointsNone |
10997 |
6. Filter based on genotype QC (FinnGen only) |
10552 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
Special
KRA_PSY_ANYMENTAL_SUICID
First used in FinnGen datafreeze
DF4
Similar endpoints
↥List of similar endpoints to
Suicide or other Intentional self-harm
based on the number of shared cases.
Similar with more cases:
- Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders
- Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders
- Any mental disorder
- External causes of morbidity and mortality
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 138951 | 58818 | 78203 |
| Only index persons | 91326 | 47745 | 43581 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.97 | 1.68 | 2.18 |
| Only index persons | 1.71 | 1.76 | 1.66 |
| Median age at first event (years) | |||
| Whole population | 36.64 | 34.70 | 37.86 |
| Only index persons | 33.80 | 32.09 | 35.68 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 10552 | 6303 | 4249 |
| Unadjusted period prevalence (%) | 2.34 | 2.48 | 2.13 |
| Median age at first event (years) | 34.67 | 32.19 | 38.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint VWXY20_SUICI_OTHER_INTENTI_SELF_H and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| VWXY20_SUICI_OTHER_INTENTI_SELF_H | 3.695 [3.29, 4.14] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.067 |
During the follow-up period (1.1.1998 — 31.12.2019), 4759 out of 37749 females with VWXY20_SUICI_OTHER_INTENTI_SELF_H died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| VWXY20_SUICI_OTHER_INTENTI_SELF_H | 4.866 [4.37, 5.41] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 7574 out of 33177 males with VWXY20_SUICI_OTHER_INTENTI_SELF_H died.
Mortality risk
Mortality risk for people of age
years, who have VWXY20_SUICI_OTHER_INTENTI_SELF_H.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.287% | 0.765% |
| 5 | 2.021% | 5.465% |
| 10 | 4.774% | 13.167% |
| 15 | 9.12% | 23.946% |
| 20 | 15.312% | 37.677% |
Relationships between endpoints
↥Index endpoint: VWXY20_SUICI_OTHER_INTENTI_SELF_H – Suicide or other Intentional self-harm
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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