No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
663 |
4. Check minimum number of eventsNone |
663 |
5. Include endpointsNone |
663 |
6. Filter based on genotype QC (FinnGen only) |
626 |
Control definitions (FinnGen only)
Control exclude
ASTHMA_PNEUMONIA
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Viral pneumonia (known virus, not influenza)
based on the number of shared cases.
Similar with more cases:
- Pneumonias (Asthma/COPD co-morbidities)
- COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia
- COPD/asthma related pneumonia or pneumonia derived septicaemia
- COPD/asthma/ILD related infections
- COPD/asthma related infections
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7453 | 3529 | 3892 |
| Only index persons | 5766 | 2742 | 3024 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.10 | 0.11 |
| Only index persons | 0.11 | 0.10 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 29.10 | 37.36 | 21.47 |
| Only index persons | 53.85 | 61.94 | 46.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 626 | 288 | 338 |
| Unadjusted period prevalence (%) | 0.14 | 0.11 | 0.17 |
| Median age at first event (years) | 65.43 | 62.09 | 68.28 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint VIRALPNEUMOKNOWN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| VIRALPNEUMOKNOWN | 3.187 [2.11, 4.8] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.755 |
During the follow-up period (1.1.1998 — 31.12.2019), 411 out of 2247 females with VIRALPNEUMOKNOWN died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| VIRALPNEUMOKNOWN | 3.92 [2.56, 6.01] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 456 out of 2423 males with VIRALPNEUMOKNOWN died.
Mortality risk
Mortality risk for people of age
years, who have VIRALPNEUMOKNOWN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.264% | 0.744% |
| 5 | 1.961% | 4.201% |
| 10 | 5.172% | 9.987% |
| 15 | 9.739% | 17.464% |
| 20 | 16.718% | 27.906% |
Relationships between endpoints
↥Index endpoint: VIRALPNEUMOKNOWN – Viral pneumonia (known virus, not influenza)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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