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Sub-endpoint used in defining T1D endpoints

T1D_ICD9_10

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E10
  • Hospital discharge: ICD-9 250
  • Cause of death: ICD-10 E10
  • Cause of death: ICD-9 250

2 out of 7 registries used, show all original rules.

14917

4. Check minimum number of events

None

14917

5. Include endpoints

None

14917

6. Filter based on genotype QC (FinnGen only)

14376

Control definitions (FinnGen only)

Control exclude T1D_STRICT1

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 E10-E14
Name in latin Diabetes (mellitus) juvenilis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 14376 6471 7905
Unadjusted period prevalence (%) 3.33 2.54 3.97
Median age at first event (years) 40.16 34.57 44.74

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: T1D_ICD9_10 – Sub-endpoint used in defining T1D endpoints

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).