Type1 diabetes, definitions combined, early onset

T1D_EARLY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE < 20

Registry filters:

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

3025

6. Filter based on genotype QC (FinnGen only)

2947

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 2947 1542 1405
Unadjusted period prevalence (%) 0.65 0.61 0.71
Median age at first event (years) 9.83 9.79 9.87

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: T1D_EARLY – Type1 diabetes, definitions combined, early onset

GWS hits: 24

This endpoint is excluded (different definition than used in FinnGen).