This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
21 |
4. Check minimum number of eventsNone |
21 |
5. Include endpointsNone |
21 |
6. Filter based on genotype QC (FinnGen only) |
20 |
Control definitions (FinnGen only)
Control exclude
CIRRHOSIS_BROAD
Extra metadata
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K74
Name in latin
Sclerosis hepatis
Similar endpoints
↥List of similar endpoints to
Sclerosis of liver
based on the number of shared cases.
Similar with more cases:
- Fibrosis and cirrhosis of liver
- Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523
- Diseases of liver
- Gastrointestinal diseases
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 158 | 84 | 73 |
| Only index persons | 120 | 63 | 57 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 62.21 | 64.42 | 59.99 |
| Only index persons | 62.24 | 62.95 | 61.45 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 20 | 14 | 6 |
| Unadjusted period prevalence (%) | 0.00 | 0.01 | 0.00 |
| Median age at first event (years) | 63.75 | 63.55 | 64.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint SCLEROLIV and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have SCLEROLIV.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: SCLEROLIV – Sclerosis of liver
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data