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Symptoms and signs involving the nervous and musculoskeletal systems

R18_SYMPTOMS_SIGNS_INVOLVI_NERVOUS_MUSCULOS_SYSTEMS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 R25-R29
  • Cause of death: ICD-10 R25-R29

2 out of 7 registries used, show all original rules.

26508

4. Check minimum number of events

None

26508

5. Include endpoints

26508

6. Filter based on genotype QC (FinnGen only)

25696

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF4
Parent code in ICD-10 R
Name in latin Symptomata et signa ad systema nervosum et systema musculosceletale pertinentia

Similar endpoints

List of similar endpoints to Symptoms and signs involving the nervous and musculoskeletal systems based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 25696 15014 10682
Unadjusted period prevalence (%) 5.68 5.90 5.36
Median age at first event (years) 56.04 51.96 61.78

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: R18_SYMPTOMS_SIGNS_INVOLVI_NERVOUS_MUSCULOS_SYSTEMS – Symptoms and signs involving the nervous and musculoskeletal systems

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).