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Malaise and fatigue

MESH Endpoint Browser

R18_MALAI_FATIG

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — R53
  • Hospital discharge: ICD-9 — 7807
  • Hospital discharge: ICD-8 — 79010
  • Cause of death: ICD-10 — R53
  • Cause of death: ICD-9 — 7807
  • Cause of death: ICD-8 — 79010

2 out of 7 registries used, show all original rules.

25231

4. Check minimum number of events

None

25231

5. Include endpoints

None

25231

6. Filter based on genotype QC (FinnGen only)

24275

Control definitions (FinnGen only)

Control exclude R18_GENERAL_SYMPTOMS_SIGNS

Extra metadata

Level in the ICD hierarchy 3
Special FATIGUE
First used in FinnGen datafreeze DF4
Parent code in ICD-10 R50-R69
Name in latin Aegritudo et lassitudo

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 24275 13451 10824
Unadjusted period prevalence (%) 5.35 5.28 5.44
Median age at first event (years) 69.82 66.86 73.50

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: R18_MALAI_FATIG – Malaise and fatigue

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).