No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
8182 |
4. Check minimum number of eventsNone |
8182 |
5. Include endpointsNone |
8182 |
6. Filter based on genotype QC (FinnGen only) |
7808 |
Control definitions (FinnGen only)
Control exclude
ASTHMA_ALLERG
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Pollen allergy
based on the number of shared cases.
Similar with more cases:
- Allergic rhinitis
- Vasomotor and allergic rhinitis
- Other diseases of upper respiratory tract
- Other pulmonary diagnosis
- Excluding asthma or asthma-COPD overlap
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 108129 | 50206 | 57693 |
| Only index persons | 94109 | 45353 | 48756 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.53 | 1.44 | 1.61 |
| Only index persons | 1.77 | 1.67 | 1.86 |
| Median age at first event (years) | |||
| Whole population | 14.16 | 17.11 | 11.52 |
| Only index persons | 16.22 | 19.74 | 12.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7808 | 5359 | 2449 |
| Unadjusted period prevalence (%) | 1.83 | 2.10 | 1.23 |
| Median age at first event (years) | 30.89 | 31.76 | 28.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint POLLENALLERG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| POLLENALLERG | 0.829 [0.7, 0.98] | 0.031 |
| Birth year | 0.998 [0.99, 1.01] | 0.672 |
During the follow-up period (1.1.1998 — 31.12.2019), 503 out of 42785 females with POLLENALLERG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| POLLENALLERG | 0.69 [0.59, 0.81] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.052 |
During the follow-up period (1.1.1998 — 31.12.2019), 571 out of 48491 males with POLLENALLERG died.
Mortality risk
Mortality risk for people of age
years, who have POLLENALLERG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.073% | 0.129% |
| 5 | 0.511% | 0.928% |
| 10 | 1.317% | 2.246% |
| 15 | 2.714% | 4.4% |
| 20 | 4.576% | 7.364% |
Relationships between endpoints
↥Index endpoint: POLLENALLERG – Pollen allergy
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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