No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
14453 |
4. Check minimum number of eventsNone |
14453 |
5. Include endpointsNone |
14453 |
6. Filter based on genotype QC (FinnGen only) |
13846 |
Control definitions (FinnGen only)
Control exclude
ASTHMA_ALLERG, ST19_ADVER_EFFEC_NOT_ELSEW_CLASSIFIED
Extra metadata
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Allergic rhinitis
based on the number of shared cases.
Similar with more cases:
- Vasomotor and allergic rhinitis
- Other diseases of upper respiratory tract
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 167729 | 82728 | 84603 |
| Only index persons | 149469 | 76134 | 73335 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.36 | 2.37 | 2.36 |
| Only index persons | 2.80 | 2.80 | 2.80 |
| Median age at first event (years) | |||
| Whole population | 19.13 | 24.99 | 13.33 |
| Only index persons | 21.15 | 27.10 | 14.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 13846 | 9407 | 4439 |
| Unadjusted period prevalence (%) | 3.22 | 3.69 | 2.23 |
| Median age at first event (years) | 34.61 | 34.93 | 33.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint ALLERG_RHINITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ALLERG_RHINITIS | 0.889 [0.78, 1.02] | 0.088 |
| Birth year | 0.992 [0.98, 1.0] | 0.076 |
During the follow-up period (1.1.1998 — 31.12.2019), 1381 out of 66401 females with ALLERG_RHINITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ALLERG_RHINITIS | 0.751 [0.66, 0.85] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.029 |
During the follow-up period (1.1.1998 — 31.12.2019), 1357 out of 66764 males with ALLERG_RHINITIS died.
Mortality risk
Mortality risk for people of age
years, who have ALLERG_RHINITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.062% | 0.131% |
| 5 | 0.516% | 0.934% |
| 10 | 1.296% | 2.347% |
| 15 | 2.308% | 4.425% |
| 20 | 3.898% | 7.773% |
Relationships between endpoints
↥Index endpoint: ALLERG_RHINITIS – Allergic rhinitis
GWS hits: 12
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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