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Fetus and newborn affected by noxious influences transmitted via placenta or breast milk

P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P04
  • Cause of death: ICD-10 P04

2 out of 7 registries used, show all original rules.

34

4. Check minimum number of events

None

34

5. Include endpoints

None

34

6. Filter based on genotype QC (FinnGen only)

32

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 P0[0-4]
Name in latin Fetus et neonatus influentiis noxiis per placentam sive lac maternum translatis affectus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3798 1782 2014
Only index persons 1275 630 645
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.06
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 0.02 0.00 0.00
Only index persons 0.04 0.07 0.01

-FinnGen-

Key figures

All Female Male
Number of individuals 32 14 18
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 0.04 0.08 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_FET_NEWB_NOXIO_INFLUENCES_TRANSMIT_PLACEN_BREAST_MILK – Fetus and newborn affected by noxious influences transmitted via placenta or breast milk

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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