No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
427 |
4. Check minimum number of eventsNone |
427 |
5. Include endpointsNone |
427 |
6. Filter based on genotype QC (FinnGen only) |
417 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
HSIL lesion of the vagina
based on the number of shared cases.
Similar with more cases:
- All dysplastic lesions of the vagina
- HSIL lesion of the cervix uteri, vagina or vulva
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2714 | 2714 | - |
| Only index persons | 2571 | 2571 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | - |
| Only index persons | 0.09 | 0.09 | - |
| Median age at first event (years) | |||
| Whole population | - | 49.94 | - |
| Only index persons | - | 48.76 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 417 | 417 | - |
| Unadjusted period prevalence (%) | 0.16 | 0.16 | - |
| Median age at first event (years) | 50.40 | 50.40 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint N14_VAGINAL_HSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_VAGINAL_HSIL | 1.265 [1.08, 1.48] | 0.003 |
| Birth year | 0.998 [0.99, 1.01] | 0.566 |
During the follow-up period (1.1.1998 — 31.12.2019), 266 out of 2226 females with N14_VAGINAL_HSIL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_VAGINAL_HSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.089% | No data |
| 5 | 0.774% | No data |
| 10 | 1.998% | No data |
| 15 | 3.721% | No data |
| 20 | 6.738% | No data |
Relationships between endpoints
↥Index endpoint: N14_VAGINAL_HSIL – HSIL lesion of the vagina
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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