No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
345 |
4. Check minimum number of eventsNone |
345 |
5. Include endpointsNone |
345 |
6. Filter based on genotype QC (FinnGen only) |
332 |
Control definitions (FinnGen only)
Control exclude
N14_BREAST
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
N60-N64
Name in latin
Aliae morbositates mammae
Similar endpoints
↥List of similar endpoints to
Galactorrhea
based on the number of shared cases.
Similar with more cases:
- Other disorders of breast
- Disorders of breast
- Exclusions for E4_PCOS_CONSORTIUM
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2252 | 2252 | - |
| Only index persons | 2207 | 2207 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | - |
| Only index persons | 0.08 | 0.08 | - |
| Median age at first event (years) | |||
| Whole population | - | 34.59 | - |
| Only index persons | - | 34.51 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 332 | 332 | - |
| Unadjusted period prevalence (%) | 0.13 | 0.13 | - |
| Median age at first event (years) | 33.99 | 33.99 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint N14_GALACTORRHEA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_GALACTORRHEA | 1.223 [0.94, 1.58] | 0.127 |
| Birth year | 0.998 [0.99, 1.01] | 0.625 |
During the follow-up period (1.1.1998 — 31.12.2019), 61 out of 1805 females with N14_GALACTORRHEA died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_GALACTORRHEA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.156% | No data |
| 5 | 0.657% | No data |
| 10 | 1.85% | No data |
| 15 | 3.8% | No data |
| 20 | 6.645% | No data |
Relationships between endpoints
↥Index endpoint: N14_GALACTORRHEA – Galactorrhea
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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