breast disease: A disease involving the breast.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4611 |
4. Check minimum number of eventsNone |
4611 |
5. Include endpoints |
4649 |
6. Filter based on genotype QC (FinnGen only) |
4440 |
Control definitions (FinnGen only)
Extra metadata
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 30304 | 30304 | - |
Only index persons | 28891 | 28891 | - |
Unadjusted period prevalence (%) | |||
Whole population | 0.87 | 0.87 | - |
Only index persons | 1.06 | 1.06 | - |
Median age at first event (years) | |||
Whole population | - | 45.19 | - |
Only index persons | - | 44.88 | - |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 4440 | 4440 | - |
Unadjusted period prevalence (%) | 1.74 | 1.74 | - |
Median age at first event (years) | 47.28 | 47.28 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_BREASTDISOTH and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
N14_BREASTDISOTH | 1.077 [0.97, 1.19] | 0.158 |
Birth year | 1.0 [0.99, 1.01] | 0.995 |
During the follow-up period (1.1.1998 — 31.12.2019), 1651 out of 19347 females with N14_BREASTDISOTH died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_BREASTDISOTH.N-year risk | Females | Males |
---|---|---|
1 | 0.101% | No data |
5 | 0.608% | No data |
10 | 1.64% | No data |
15 | 3.322% | No data |
20 | 6.147% | No data |
Relationships between endpoints
↥Index endpoint: N14_BREASTDISOTH – Other disorders of breast
GWS hits: -