No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
7298 |
4. Check minimum number of eventsNone |
7298 |
5. Include endpointsNone |
7298 |
6. Filter based on genotype QC (FinnGen only) |
6977 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Similar endpoints
↥List of similar endpoints to HSIL lesion of the cervix uteri based on the number of shared cases.
Similar with more cases:
- HSIL lesion of the cervix uteri, vagina or vulva
- All dysplastic lesions of the cervix uteri
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 53171 | 53171 | - |
Only index persons | 51989 | 51989 | - |
Unadjusted period prevalence (%) | |||
Whole population | 1.52 | 1.52 | - |
Only index persons | 1.91 | 1.91 | - |
Median age at first event (years) | |||
Whole population | - | 34.59 | - |
Only index persons | - | 34.40 | - |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 6977 | 6977 | - |
Unadjusted period prevalence (%) | 2.74 | 2.74 | - |
Median age at first event (years) | 35.11 | 35.11 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_CERVICAL_HSIL and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
N14_CERVICAL_HSIL | 1.314 [1.17, 1.48] | < 0.001 |
Birth year | 0.991 [0.98, 1.0] | 0.045 |
During the follow-up period (1.1.1998 — 31.12.2019), 1401 out of 43721 females with N14_CERVICAL_HSIL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_CERVICAL_HSIL.N-year risk | Females | Males |
---|---|---|
1 | 0.103% | No data |
5 | 0.634% | No data |
10 | 1.524% | No data |
15 | 3.107% | No data |
20 | 5.718% | No data |
Relationships between endpoints
↥Index endpoint: N14_CERVICAL_HSIL – HSIL lesion of the cervix uteri
GWS hits: 4