Tibial collateral bursitis [Pellegrini-Stieda]

M13_TIBIALCOLLATERAL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M76.4
  • Hospital discharge: ICD-9 7266B|7266C
  • Cause of death: ICD-10 M76.4
  • Cause of death: ICD-9 7266B|7266C

2 out of 7 registries used, show all original rules.

358

4. Check minimum number of events

None

358

5. Include endpoints

None

358

6. Filter based on genotype QC (FinnGen only)

346

Control definitions (FinnGen only)

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M76
Name in latin Bursitis anserina

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2376 1534 838
Only index persons 2289 1496 793
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.02
Only index persons 0.05 0.05 0.03
Median age at first event (years)
Whole population 51.13 54.01 45.92
Only index persons 50.96 53.82 45.56

-FinnGen-

Key figures

All Female Male
Number of individuals 346 241 105
Unadjusted period prevalence (%) 0.08 0.09 0.05
Median age at first event (years) 53.49 54.51 51.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint M13_TIBIALCOLLATERAL and mortality.

Females

Parameter HR [95% CI] p-value
M13_TIBIALCOLLATERAL 0.731 [0.58, 0.92] 0.008
Birth year 0.995 [0.99, 1.0] 0.297

During the follow-up period (1.1.1998 — 31.12.2019), 86 out of 1195 females with M13_TIBIALCOLLATERAL died.

Males

Parameter HR [95% CI] p-value
M13_TIBIALCOLLATERAL 1.153 [0.89, 1.5] 0.286
Birth year 0.989 [0.98, 1.0] 0.031

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 529 males with M13_TIBIALCOLLATERAL died.

Mortality risk

Mortality risk for people of age

years, who have M13_TIBIALCOLLATERAL.

N-year risk Females Males
1 0.061% 0.217%
5 0.427% 1.509%
10 1.123% 3.654%
15 2.112% 6.848%
20 3.733% 12.032%

Relationships between endpoints

Index endpoint: M13_TIBIALCOLLATERAL – Tibial collateral bursitis [Pellegrini-Stieda]

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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