No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
81 |
4. Check minimum number of eventsNone |
81 |
5. Include endpointsNone |
81 |
6. Filter based on genotype QC (FinnGen only) |
79 |
Control definitions (FinnGen only)
Control exclude
M13_DORSOPATHY
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M48
Name in latin
Spondylopathia traumatica
Similar endpoints
↥List of similar endpoints to
Traumatic spondylopathy
based on the number of shared cases.
Similar with more cases:
- Spondylopathies
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 861 | 449 | 403 |
| Only index persons | 672 | 376 | 296 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 59.90 | 63.11 | 56.48 |
| Only index persons | 59.56 | 62.52 | 55.79 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 79 | 46 | 33 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 54.65 | 55.53 | 53.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_SPONDYLOTRAUM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SPONDYLOTRAUM | 1.502 [1.12, 2.01] | 0.006 |
| Birth year | 0.994 [0.99, 1.0] | 0.184 |
During the follow-up period (1.1.1998 — 31.12.2019), 103 out of 278 females with M13_SPONDYLOTRAUM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SPONDYLOTRAUM | 1.588 [1.09, 2.31] | 0.015 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 217 males with M13_SPONDYLOTRAUM died.
Mortality risk
Mortality risk for people of age
years, who have M13_SPONDYLOTRAUM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | 0.327% |
| 5 | 0.726% | 2.047% |
| 10 | 2.085% | 4.789% |
| 15 | 4.192% | 8.912% |
| 20 | 7.266% | 14.514% |
Relationships between endpoints
↥Index endpoint: M13_SPONDYLOTRAUM – Traumatic spondylopathy
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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