No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2873 |
4. Check minimum number of eventsNone |
2873 |
5. Include endpointsNone |
2873 |
6. Filter based on genotype QC (FinnGen only) |
2776 |
Control definitions (FinnGen only)
Control exclude
M13_ARTHROPATHIES
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M24
Name in latin
Luxatio sive subluxatio articulationis recurrens
Similar endpoints
↥List of similar endpoints to
Recurrent dislocation and subluxation of joint
based on the number of shared cases.
Similar with more cases:
- Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 26844 | 11969 | 14746 |
| Only index persons | 25037 | 11129 | 13908 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.38 | 0.34 | 0.41 |
| Only index persons | 0.48 | 0.41 | 0.53 |
| Median age at first event (years) | |||
| Whole population | 29.55 | 31.90 | 27.59 |
| Only index persons | 28.78 | 30.81 | 27.15 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2776 | 1610 | 1166 |
| Unadjusted period prevalence (%) | 0.61 | 0.63 | 0.59 |
| Median age at first event (years) | 32.01 | 32.13 | 31.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_RECUDISLOCATIO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_RECUDISLOCATIO | 1.41 [1.23, 1.62] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.622 |
During the follow-up period (1.1.1998 — 31.12.2019), 421 out of 6373 females with M13_RECUDISLOCATIO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_RECUDISLOCATIO | 1.426 [1.25, 1.62] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 478 out of 9356 males with M13_RECUDISLOCATIO died.
Mortality risk
Mortality risk for people of age
years, who have M13_RECUDISLOCATIO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.162% | 0.246% |
| 5 | 0.928% | 1.471% |
| 10 | 2.022% | 3.495% |
| 15 | 3.939% | 6.501% |
| 20 | 7.274% | 10.864% |
Relationships between endpoints
↥Index endpoint: M13_RECUDISLOCATIO – Recurrent dislocation and subluxation of joint
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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