Peroneal tendinitis

M13_PERONEALTEND

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M76.7
  • Cause of death: ICD-10 M76.7

2 out of 7 registries used, show all original rules.

502

4. Check minimum number of events

None

502

5. Include endpoints

None

502

6. Filter based on genotype QC (FinnGen only)

482

Control definitions (FinnGen only)

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M76
Name in latin Tendinitis peronea

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3180 2043 1125
Only index persons 3138 2032 1106
Unadjusted period prevalence (%)
Whole population 0.05 0.06 0.03
Only index persons 0.06 0.07 0.04
Median age at first event (years)
Whole population 51.56 51.89 50.97
Only index persons 51.56 51.87 50.97

-FinnGen-

Key figures

All Female Male
Number of individuals 482 356 126
Unadjusted period prevalence (%) 0.12 0.14 0.06
Median age at first event (years) 54.50 53.72 56.73

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint M13_PERONEALTEND and mortality.

Females

Parameter HR [95% CI] p-value
M13_PERONEALTEND 0.781 [0.6, 1.01] 0.059
Birth year 0.994 [0.98, 1.01] 0.318

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 1548 females with M13_PERONEALTEND died.

Males

Parameter HR [95% CI] p-value
M13_PERONEALTEND 0.976 [0.75, 1.27] 0.857
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 851 males with M13_PERONEALTEND died.

Mortality risk

Mortality risk for people of age

years, who have M13_PERONEALTEND.

N-year risk Females Males
1 0.071% 0.197%
5 0.451% 1.111%
10 1.115% 2.495%
15 2.087% 4.866%
20 3.869% 8.416%

Relationships between endpoints

Index endpoint: M13_PERONEALTEND – Peroneal tendinitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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