No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2105 |
4. Check minimum number of eventsNone |
2105 |
5. Include endpointsNone |
2105 |
6. Filter based on genotype QC (FinnGen only) |
2035 |
Control definitions (FinnGen only)
Control exclude
M13_ARTHROPATHIES
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Recurrent dislocation of patella
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19797 | 13168 | 6579 |
| Only index persons | 19426 | 12963 | 6463 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.31 | 0.38 | 0.18 |
| Only index persons | 0.40 | 0.48 | 0.25 |
| Median age at first event (years) | |||
| Whole population | 23.12 | 23.50 | 22.33 |
| Only index persons | 23.08 | 23.49 | 22.26 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2035 | 1615 | 420 |
| Unadjusted period prevalence (%) | 0.55 | 0.63 | 0.21 |
| Median age at first event (years) | 28.10 | 27.85 | 29.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_PATELLADISLOCATIO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_PATELLADISLOCATIO | 1.193 [0.99, 1.43] | 0.058 |
| Birth year | 0.996 [0.99, 1.0] | 0.374 |
During the follow-up period (1.1.1998 — 31.12.2019), 275 out of 11267 females with M13_PATELLADISLOCATIO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_PATELLADISLOCATIO | 1.027 [0.87, 1.22] | 0.757 |
| Birth year | 0.99 [0.98, 1.0] | 0.046 |
During the follow-up period (1.1.1998 — 31.12.2019), 184 out of 5661 males with M13_PATELLADISLOCATIO died.
Mortality risk
Mortality risk for people of age
years, who have M13_PATELLADISLOCATIO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.126% | 0.229% |
| 5 | 0.735% | 1.165% |
| 10 | 1.84% | 3.124% |
| 15 | 3.696% | 5.729% |
| 20 | 6.432% | 9.717% |
Relationships between endpoints
↥Index endpoint: M13_PATELLADISLOCATIO – Recurrent dislocation of patella
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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