No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
6840 |
4. Check minimum number of eventsNone |
6840 |
5. Include endpointsNone |
6840 |
6. Filter based on genotype QC (FinnGen only) |
6622 |
Control definitions (FinnGen only)
Control exclude
M13_ARTHROPATHIES
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M20
Name in latin
Alii digiti malleiformes [acquisiti] pedis
Similar endpoints
↥List of similar endpoints to
Other hammer toe(s) (acquired)
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 50340 | 40345 | 9734 |
| Only index persons | 44622 | 36116 | 8506 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.98 | 1.16 | 0.27 |
| Only index persons | 1.14 | 1.33 | 0.32 |
| Median age at first event (years) | |||
| Whole population | 61.25 | 61.26 | 61.22 |
| Only index persons | 60.93 | 60.97 | 60.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6622 | 5263 | 1359 |
| Unadjusted period prevalence (%) | 1.78 | 2.07 | 0.68 |
| Median age at first event (years) | 60.90 | 60.52 | 62.35 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_HAMMERTOE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_HAMMERTOE | 0.791 [0.73, 0.86] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.176 |
During the follow-up period (1.1.1998 — 31.12.2019), 3634 out of 25503 females with M13_HAMMERTOE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_HAMMERTOE | 1.026 [0.93, 1.14] | 0.626 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 1472 out of 6703 males with M13_HAMMERTOE died.
Mortality risk
Mortality risk for people of age
years, who have M13_HAMMERTOE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.091% | 0.181% |
| 5 | 0.486% | 1.162% |
| 10 | 1.196% | 2.92% |
| 15 | 2.377% | 5.763% |
| 20 | 4.184% | 9.387% |
Relationships between endpoints
↥Index endpoint: M13_HAMMERTOE – Other hammer toe(s) (acquired)
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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