No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
18022 |
4. Check minimum number of eventsNone |
18022 |
5. Include endpointsNone |
18022 |
6. Filter based on genotype QC (FinnGen only) |
17421 |
Control definitions (FinnGen only)
Control exclude
M13_ARTHROPATHIES
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
M20
Name in latin
Hallux valgus (acquisitus)
Similar endpoints
↥List of similar endpoints to
Hallux valgus (acquired)
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 149065 | 128378 | 19941 |
| Only index persons | 131660 | 114441 | 17219 |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.25 | 3.68 | 0.56 |
| Only index persons | 3.74 | 4.21 | 0.66 |
| Median age at first event (years) | |||
| Whole population | 53.59 | 53.33 | 55.17 |
| Only index persons | 52.82 | 52.57 | 54.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 17421 | 14976 | 2445 |
| Unadjusted period prevalence (%) | 5.23 | 5.88 | 1.23 |
| Median age at first event (years) | 52.29 | 51.65 | 56.22 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_HALLUXVALGUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_HALLUXVALGUS | 0.775 [0.72, 0.84] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.085 |
During the follow-up period (1.1.1998 — 31.12.2019), 5306 out of 60349 females with M13_HALLUXVALGUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_HALLUXVALGUS | 0.855 [0.78, 0.94] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 1933 out of 11831 males with M13_HALLUXVALGUS died.
Mortality risk
Mortality risk for people of age
years, who have M13_HALLUXVALGUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.067% | 0.179% |
| 5 | 0.395% | 1.086% |
| 10 | 1.01% | 2.694% |
| 15 | 1.872% | 5.059% |
| 20 | 3.424% | 8.185% |
Relationships between endpoints
↥Index endpoint: M13_HALLUXVALGUS – Hallux valgus (acquired)
GWS hits: 46
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data