No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
267 |
4. Check minimum number of eventsNone |
267 |
5. Include endpointsNone |
267 |
6. Filter based on genotype QC (FinnGen only) |
259 |
Control definitions (FinnGen only)
Control exclude
M13_ARTHROPATHIES
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M20
Name in latin
Alia deformitas hallucis [acquisita]
Similar endpoints
↥List of similar endpoints to
Other deformity of hallux (acquired)
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1768 | 1316 | 446 |
| Only index persons | 1661 | 1261 | 400 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.01 |
| Only index persons | 0.04 | 0.05 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 56.00 | 56.11 | 55.53 |
| Only index persons | 55.69 | 55.82 | 55.28 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 259 | 205 | 54 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.03 |
| Median age at first event (years) | 55.08 | 54.04 | 59.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_HALLUDEFORMOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_HALLUDEFORMOTH | 0.675 [0.54, 0.85] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.581 |
During the follow-up period (1.1.1998 — 31.12.2019), 85 out of 970 females with M13_HALLUDEFORMOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_HALLUDEFORMOTH | 0.93 [0.7, 1.24] | 0.625 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 341 males with M13_HALLUDEFORMOTH died.
Mortality risk
Mortality risk for people of age
years, who have M13_HALLUDEFORMOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.058% | 0.114% |
| 5 | 0.403% | 1.004% |
| 10 | 1.009% | 2.475% |
| 15 | 2.078% | 4.616% |
| 20 | 3.681% | 7.893% |
Relationships between endpoints
↥Index endpoint: M13_HALLUDEFORMOTH – Other deformity of hallux (acquired)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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