No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
207 |
4. Check minimum number of eventsNone |
207 |
5. Include endpointsNone |
207 |
6. Filter based on genotype QC (FinnGen only) |
196 |
Control definitions (FinnGen only)
Control exclude
M13_ARTHROPATHIES
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Deformity of finger(s)
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1492 | 854 | 627 |
| Only index persons | 1395 | 803 | 592 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 50.52 | 50.87 | 49.88 |
| Only index persons | 50.09 | 50.51 | 49.51 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 196 | 112 | 84 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 51.88 | 49.85 | 54.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_FINGERDEFORM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_FINGERDEFORM | 1.24 [0.96, 1.6] | 0.096 |
| Birth year | 0.999 [0.99, 1.01] | 0.752 |
During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 690 females with M13_FINGERDEFORM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_FINGERDEFORM | 1.117 [0.87, 1.43] | 0.381 |
| Birth year | 0.991 [0.98, 1.0] | 0.189 |
During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 494 males with M13_FINGERDEFORM died.
Mortality risk
Mortality risk for people of age
years, who have M13_FINGERDEFORM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.155% | 0.254% |
| 5 | 0.81% | 1.674% |
| 10 | 2.038% | 3.989% |
| 15 | 3.924% | 7.081% |
| 20 | 6.915% | 11.933% |
Relationships between endpoints
↥Index endpoint: M13_FINGERDEFORM – Deformity of finger(s)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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