No definition available.
Other/unspecified enthesopathies of lower limb, excluding foot
EFO MESH Endpoint Browser PheWeb
M13_ENTESOPATHYLOWNAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2719 |
4. Check minimum number of eventsNone |
2719 |
5. Include endpointsNone |
2719 |
6. Filter based on genotype QC (FinnGen only) |
2629 |
Control definitions (FinnGen only)
Control exclude
M13_DORSOPATHY
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other/unspecified enthesopathies of lower limb, excluding foot
based on the number of shared cases.
Similar with more cases:
- Enthesopathies of lower limb, excluding foot
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19066 | 11159 | 7830 |
| Only index persons | 18272 | 10791 | 7481 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.28 | 0.32 | 0.22 |
| Only index persons | 0.35 | 0.40 | 0.29 |
| Median age at first event (years) | |||
| Whole population | 45.48 | 49.99 | 39.01 |
| Only index persons | 45.16 | 49.69 | 38.62 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2629 | 1763 | 866 |
| Unadjusted period prevalence (%) | 0.61 | 0.69 | 0.43 |
| Median age at first event (years) | 50.80 | 51.20 | 50.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_ENTESOPATHYLOWNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ENTESOPATHYLOWNAS | 1.184 [1.06, 1.33] | 0.004 |
| Birth year | 0.991 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 1019 out of 9037 females with M13_ENTESOPATHYLOWNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ENTESOPATHYLOWNAS | 1.203 [1.06, 1.36] | 0.003 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 689 out of 5860 males with M13_ENTESOPATHYLOWNAS died.
Mortality risk
Mortality risk for people of age
years, who have M13_ENTESOPATHYLOWNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.101% | 0.218% |
| 5 | 0.636% | 1.265% |
| 10 | 1.486% | 3.29% |
| 15 | 2.856% | 6.41% |
| 20 | 5.179% | 10.96% |
Relationships between endpoints
↥Index endpoint: M13_ENTESOPATHYLOWNAS – Other/unspecified enthesopathies of lower limb, excluding foot
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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