brachial plexus neuritis: An inflammatory process affecting the brachial plexus. It results in severe pain in the upper extremity and shoulder, upper arm weakness and loss of sensation in the upper arm.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
9571 |
4. Check minimum number of eventsNone |
9571 |
5. Include endpointsNone |
9571 |
6. Filter based on genotype QC (FinnGen only) |
9185 |
Control definitions (FinnGen only)
Control exclude
M13_DORSOPATHY
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M53
Name in latin
Syndroma cervicobrachiale
Similar endpoints
↥List of similar endpoints to
Cervicobrachial syndrome
based on the number of shared cases.
Similar with more cases:
- Other dorsopathies, not elsewhere classified
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 72250 | 45144 | 26648 |
| Only index persons | 66877 | 42653 | 24224 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.09 | 1.29 | 0.74 |
| Only index persons | 1.34 | 1.57 | 0.92 |
| Median age at first event (years) | |||
| Whole population | 51.01 | 50.95 | 51.16 |
| Only index persons | 50.46 | 50.42 | 50.54 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9185 | 6232 | 2953 |
| Unadjusted period prevalence (%) | 2.14 | 2.45 | 1.48 |
| Median age at first event (years) | 50.90 | 49.93 | 52.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_CERVICOBRACHSDR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CERVICOBRACHSDR | 0.903 [0.81, 1.0] | 0.06 |
| Birth year | 0.994 [0.99, 1.0] | 0.177 |
During the follow-up period (1.1.1998 — 31.12.2019), 2228 out of 33570 females with M13_CERVICOBRACHSDR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CERVICOBRACHSDR | 0.938 [0.85, 1.03] | 0.188 |
| Birth year | 0.991 [0.98, 1.0] | 0.054 |
During the follow-up period (1.1.1998 — 31.12.2019), 2127 out of 19733 males with M13_CERVICOBRACHSDR died.
Mortality risk
Mortality risk for people of age
years, who have M13_CERVICOBRACHSDR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.091% | 0.126% |
| 5 | 0.528% | 1.173% |
| 10 | 1.358% | 3.025% |
| 15 | 2.567% | 5.839% |
| 20 | 4.71% | 10.057% |
Relationships between endpoints
↥Index endpoint: M13_CERVICOBRACHSDR – Cervicobrachial syndrome
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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