Other bursopathies

M13_BURSOPATHY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M71
  • Cause of death: ICD-10 M71

2 out of 7 registries used, show all original rules.

4764

4. Check minimum number of events

None

4764

5. Include endpoints

5113

6. Filter based on genotype QC (FinnGen only)

4964

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M70-M79
Name in latin Aliae bursopathiae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 41296 21325 19813
Only index persons 38201 19989 18212
Unadjusted period prevalence (%)
Whole population 0.58 0.61 0.55
Only index persons 0.72 0.73 0.70
Median age at first event (years)
Whole population 56.24 59.26 52.95
Only index persons 55.55 58.55 52.26

-FinnGen-

Key figures

All Female Male
Number of individuals 4964 2703 2261
Unadjusted period prevalence (%) 1.10 1.06 1.14
Median age at first event (years) 56.58 56.67 56.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint M13_BURSOPATHY and mortality.

Females

Parameter HR [95% CI] p-value
M13_BURSOPATHY 1.064 [0.97, 1.17] 0.192
Birth year 0.992 [0.98, 1.0] 0.06

During the follow-up period (1.1.1998 — 31.12.2019), 3130 out of 16763 females with M13_BURSOPATHY died.

Males

Parameter HR [95% CI] p-value
M13_BURSOPATHY 1.175 [1.07, 1.29] 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 2784 out of 15302 males with M13_BURSOPATHY died.

Mortality risk

Mortality risk for people of age

years, who have M13_BURSOPATHY.

N-year risk Females Males
1 0.112% 0.248%
5 0.554% 1.4%
10 1.406% 3.436%
15 2.566% 6.496%
20 4.713% 10.591%

Relationships between endpoints

Index endpoint: M13_BURSOPATHY – Other bursopathies

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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