Infective bursitis

M13_INFBURSA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

951

4. Check minimum number of events

None

951

5. Include endpoints

None

951

6. Filter based on genotype QC (FinnGen only)

925

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8365 2327 6010
Only index persons 7744 2159 5585
Unadjusted period prevalence (%)
Whole population 0.14 0.07 0.17
Only index persons 0.18 0.08 0.21
Median age at first event (years)
Whole population 53.66 58.48 51.73
Only index persons 52.87 57.57 51.05

-FinnGen-

Key figures

All Female Male
Number of individuals 925 286 639
Unadjusted period prevalence (%) 0.26 0.11 0.32
Median age at first event (years) 54.66 55.13 54.45

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint M13_INFBURSA and mortality.

Females

Parameter HR [95% CI] p-value
M13_INFBURSA 1.424 [1.23, 1.65] < 0.001
Birth year 0.993 [0.98, 1.0] 0.085

During the follow-up period (1.1.1998 — 31.12.2019), 501 out of 2040 females with M13_INFBURSA died.

Males

Parameter HR [95% CI] p-value
M13_INFBURSA 1.548 [1.38, 1.73] < 0.001
Birth year 0.99 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 1088 out of 5234 males with M13_INFBURSA died.

Mortality risk

Mortality risk for people of age

years, who have M13_INFBURSA.

N-year risk Females Males
1 0.138% 0.342%
5 0.763% 2.043%
10 1.942% 4.868%
15 3.474% 9.815%
20 6.294% 15.977%

Relationships between endpoints

Index endpoint: M13_INFBURSA – Infective bursitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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