≡ Risteys
FG R11 + FR

Documentation Changelog GitHub Contact & Feedback

Other acquired deformities of ankle and foot

EFO MESH Endpoint Browser PheWeb

M13_ANKLEFOOT

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M21.6
  • Hospital discharge: ICD-9 — 7367
  • Cause of death: ICD-10 — M21.6
  • Cause of death: ICD-9 — 7367

2 out of 7 registries used, show all original rules.

258

4. Check minimum number of events

None

258

5. Include endpoints

None

258

6. Filter based on genotype QC (FinnGen only)

252

Control definitions (FinnGen only)

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M21
Name in latin Aliae deformitates acquisitae tarsi et pedis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2070 1328 732
Only index persons 1951 1272 679
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.02
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 49.53 52.51 44.04
Only index persons 49.39 52.17 44.18

-FinnGen-

Key figures

All Female Male
Number of individuals 252 179 73
Unadjusted period prevalence (%) 0.06 0.07 0.04
Median age at first event (years) 51.71 51.27 52.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

↥

Association

Association between endpoint M13_ANKLEFOOT and mortality.

Females

Parameter HR [95% CI] p-value
M13_ANKLEFOOT 0.955 [0.74, 1.23] 0.72
Birth year 0.996 [0.99, 1.0] 0.354

During the follow-up period (1.1.1998 — 31.12.2019), 83 out of 876 females with M13_ANKLEFOOT died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_ANKLEFOOT.

N-year risk Females Males
1 0.109% No data
5 0.579% No data
10 1.411% No data
15 2.842% No data
20 5.145% No data

Relationships between endpoints

↥

Index endpoint: M13_ANKLEFOOT – Other acquired deformities of ankle and foot

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data