No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4002 |
4. Check minimum number of eventsNone |
4002 |
5. Include endpointsNone |
4002 |
6. Filter based on genotype QC (FinnGen only) |
3874 |
Control definitions (FinnGen only)
Control exclude
M13_DORSOPATHY
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M76
Name in latin
Tendinitis tendinis Achillis
Similar endpoints
↥List of similar endpoints to
Achilles tendinitis
based on the number of shared cases.
Similar with more cases:
- Enthesopathies of lower limb, excluding foot
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 26379 | 12438 | 13852 |
| Only index persons | 25665 | 12199 | 13466 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.37 | 0.36 | 0.39 |
| Only index persons | 0.48 | 0.45 | 0.51 |
| Median age at first event (years) | |||
| Whole population | 50.12 | 51.73 | 48.70 |
| Only index persons | 50.02 | 51.68 | 48.51 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3874 | 2090 | 1784 |
| Unadjusted period prevalence (%) | 0.86 | 0.82 | 0.90 |
| Median age at first event (years) | 52.92 | 52.23 | 53.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_ACHILLESTEND and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ACHILLESTEND | 0.902 [0.8, 1.02] | 0.095 |
| Birth year | 0.994 [0.99, 1.0] | 0.166 |
During the follow-up period (1.1.1998 — 31.12.2019), 623 out of 9742 females with M13_ACHILLESTEND died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ACHILLESTEND | 0.776 [0.69, 0.87] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 892 out of 10400 males with M13_ACHILLESTEND died.
Mortality risk
Mortality risk for people of age
years, who have M13_ACHILLESTEND.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.06% | 0.109% |
| 5 | 0.485% | 0.708% |
| 10 | 1.193% | 1.932% |
| 15 | 2.506% | 3.762% |
| 20 | 4.409% | 6.826% |
Relationships between endpoints
↥Index endpoint: M13_ACHILLESTEND – Achilles tendinitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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