No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
85 |
4. Check minimum number of eventsNone |
85 |
5. Include endpointsNone |
85 |
6. Filter based on genotype QC (FinnGen only) |
81 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Lichenoid drug reaction
based on the number of shared cases.
Similar with more cases:
- Lichen planus
- Lichen planus, including avohilmo
- Lichen ruber planus, wide definition including periferal and oral lichen planus
- Papulosquamous disorders
- Diseases of the skin and subcutaneous tissue
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 477 | 331 | 146 |
| Only index persons | 447 | 310 | 137 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | - | 60.35 | 59.94 |
| Only index persons | 59.71 | 59.82 | 59.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 81 | 58 | 23 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 58.04 | 58.45 | 57.03 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint LICHENOID_DRUG_REACTION and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| LICHENOID_DRUG_REACTION | 1.212 [0.91, 1.62] | 0.194 |
| Birth year | 0.994 [0.99, 1.0] | 0.168 |
During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 311 females with LICHENOID_DRUG_REACTION died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have LICHENOID_DRUG_REACTION.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.102% | No data |
| 5 | 0.546% | No data |
| 10 | 1.518% | No data |
| 15 | 3.23% | No data |
| 20 | 5.826% | No data |
Relationships between endpoints
↥Index endpoint: LICHENOID_DRUG_REACTION – Lichenoid drug reaction
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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