No definition available.
Lichen ruber planus, wide definition including periferal and oral lichen planus
K11_LICHEN_PLANUS_WIDE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
7703 |
6. Filter based on genotype QC (FinnGen only) |
7450 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF10
Lichen ruber planus, wide definition including periferal and oral lichen planus
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 49313 | 31731 | 17388 |
| Only index persons | 47551 | 30823 | 16728 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.76 | 0.91 | 0.49 |
| Only index persons | 0.96 | 1.13 | 0.64 |
| Median age at first event (years) | |||
| Whole population | 59.19 | 61.01 | 56.01 |
| Only index persons | 59.11 | 60.88 | 55.84 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7450 | 5008 | 2442 |
| Unadjusted period prevalence (%) | 1.72 | 1.97 | 1.23 |
| Median age at first event (years) | 60.59 | 60.82 | 60.13 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_LICHEN_PLANUS_WIDE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_LICHEN_PLANUS_WIDE | 0.843 [0.76, 0.93] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.143 |
During the follow-up period (1.1.1998 — 31.12.2019), 2485 out of 24901 females with K11_LICHEN_PLANUS_WIDE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_LICHEN_PLANUS_WIDE | 0.832 [0.74, 0.93] | 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 1561 out of 13401 males with K11_LICHEN_PLANUS_WIDE died.
Mortality risk
Mortality risk for people of age
years, who have K11_LICHEN_PLANUS_WIDE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.077% | 0.16% |
| 5 | 0.43% | 1.002% |
| 10 | 1.069% | 2.575% |
| 15 | 2.15% | 4.734% |
| 20 | 4.047% | 8.05% |
Relationships between endpoints
↥Index endpoint: K11_LICHEN_PLANUS_WIDE – Lichen ruber planus, wide definition including periferal and oral lichen planus
GWS hits: 12
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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