No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
275 |
4. Check minimum number of eventsNone |
275 |
5. Include endpoints |
360 |
6. Filter based on genotype QC (FinnGen only) |
337 |
Control definitions (FinnGen only)
Control exclude
L12_PAPULOSQUAMOUS
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L40-L45
Name in latin
Aliae morbositates papulosquamosae
Similar endpoints
↥List of similar endpoints to
Other papulosquamous disorders
based on the number of shared cases.
Similar with more cases:
- Papulosquamous disorders
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3924 | 2160 | 1732 |
| Only index persons | 3067 | 1745 | 1322 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.05 |
| Only index persons | 0.06 | 0.06 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 43.28 | 46.71 | 38.85 |
| Only index persons | 41.53 | 44.89 | 37.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 337 | 193 | 144 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.07 |
| Median age at first event (years) | 48.32 | 43.93 | 54.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint L12_PAPULOSQUAOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PAPULOSQUAOTH | 1.183 [0.96, 1.46] | 0.119 |
| Birth year | 0.99 [0.98, 1.0] | 0.027 |
During the follow-up period (1.1.1998 — 31.12.2019), 164 out of 1235 females with L12_PAPULOSQUAOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PAPULOSQUAOTH | 1.496 [1.14, 1.97] | 0.004 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 184 out of 1017 males with L12_PAPULOSQUAOTH died.
Mortality risk
Mortality risk for people of age
years, who have L12_PAPULOSQUAOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.083% | 0.332% |
| 5 | 0.566% | 1.753% |
| 10 | 1.522% | 4.204% |
| 15 | 2.952% | 7.479% |
| 20 | 5.118% | 12.236% |
Relationships between endpoints
↥Index endpoint: L12_PAPULOSQUAOTH – Other papulosquamous disorders
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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