granuloma annulare: a fairly rare, chronic dermatological condition which presents as reddish bumps on the skin arranged in a circle or ring. It can initially occur at any age and is significantly more common in females (80/20 ratio).
Other and unspecified granulomatous disorders of skin and subcutaneous tissue
DOID EFO Endpoint Browser PheWeb
L12_GRANULOMASKINNAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
113 |
4. Check minimum number of eventsNone |
113 |
5. Include endpointsNone |
113 |
6. Filter based on genotype QC (FinnGen only) |
109 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Other and unspecified granulomatous disorders of skin and subcutaneous tissue based on the number of shared cases.
Similar with more cases:
- Granulomatous disorders of skin and subcutaneous tissue
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 993 | 626 | 359 |
Only index persons | 911 | 590 | 321 |
Unadjusted period prevalence (%) | |||
Whole population | 0.01 | 0.02 | 0.01 |
Only index persons | 0.02 | 0.02 | 0.01 |
Median age at first event (years) | |||
Whole population | 49.54 | 49.28 | 50.25 |
Only index persons | 49.87 | 49.92 | 49.78 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 109 | 77 | 32 |
Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.02 |
Median age at first event (years) | 55.01 | 53.45 | 58.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_GRANULOMASKINNAS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
L12_GRANULOMASKINNAS | 1.273 [0.96, 1.7] | 0.099 |
Birth year | 0.994 [0.99, 1.0] | 0.152 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 568 females with L12_GRANULOMASKINNAS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
L12_GRANULOMASKINNAS | 1.534 [1.1, 2.13] | 0.011 |
Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 329 males with L12_GRANULOMASKINNAS died.
Mortality risk
Mortality risk for people of age
years, who have L12_GRANULOMASKINNAS.N-year risk | Females | Males |
---|---|---|
1 | 0.155% | 0.299% |
5 | 0.743% | 1.711% |
10 | 1.917% | 4.362% |
15 | 3.524% | 8.553% |
20 | 6.092% | 14.414% |
Relationships between endpoints
↥Index endpoint: L12_GRANULOMASKINNAS – Other and unspecified granulomatous disorders of skin and subcutaneous tissue
GWS hits: -