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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Anhidrosis

L12_ANHIDROSIS

anhidrosis: the inability to sweat normally. When you don't sweat (perspire), your body can't cool itself, which can lead to overheating and sometimes to heatstroke — a potentially fatal condition. Anhidrosis— sometimes called hypohidrosis — can be difficult to diagnose.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L74.4
  • Hospital discharge: ICD-9 7050A
  • Hospital discharge: ICD-8 7050
  • Cause of death: ICD-10 L74.4
  • Cause of death: ICD-9 7050A
  • Cause of death: ICD-8 7050

2 out of 7 registries used, show all original rules.

14

4. Check minimum number of events

None

14

5. Include endpoints

None

14

6. Filter based on genotype QC (FinnGen only)

13

Control definitions (FinnGen only)

Control exclude L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L74
Name in latin Anhidrosis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 121 72 49
Only index persons 104 60 44
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 38.52 29.22
Only index persons 29.65 33.98 23.75

-FinnGen-

Key figures

All Female Male
Number of individuals 13 7 6
Unadjusted period prevalence (%) 0.00 0.00 0.00
Median age at first event (years) 40.18 38.88 41.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint L12_ANHIDROSIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_ANHIDROSIS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: L12_ANHIDROSIS – Anhidrosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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