No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
183 |
4. Check minimum number of eventsNone |
183 |
5. Include endpointsNone |
183 |
6. Filter based on genotype QC (FinnGen only) |
175 |
Control definitions (FinnGen only)
Control exclude
L12_DISORDSKINAPPENDIX
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L70
Name in latin
Acne conglobata
Similar endpoints
↥List of similar endpoints to
Acne conglobata
based on the number of shared cases.
Similar with more cases:
- Acne
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2189 | 621 | 1555 |
| Only index persons | 2136 | 611 | 1525 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.04 |
| Only index persons | 0.05 | 0.02 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 21.34 | 25.74 | 19.47 |
| Only index persons | 21.13 | 25.47 | 19.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 175 | 75 | 100 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | 28.88 | 30.97 | 27.32 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint L12_ACNE_CONGLOBLATA and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_ACNE_CONGLOBLATA | 2.188 [1.59, 3.01] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 1137 males with L12_ACNE_CONGLOBLATA died.
Mortality risk
Mortality risk for people of age
years, who have L12_ACNE_CONGLOBLATA.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.376% |
| 5 | No data | 2.552% |
| 10 | No data | 6.73% |
| 15 | No data | 12.466% |
| 20 | No data | 21.196% |
Relationships between endpoints
↥Index endpoint: L12_ACNE_CONGLOBLATA – Acne conglobata
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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