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KRA_PSY_EATING

Endpoint Browser PheWeb

KRA_PSY_EATING_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F50
  • Hospital discharge: ICD-9 — 3071|3075[ABE]
  • Hospital discharge: ICD-8 — 30650
  • Cause of death: ICD-10 — F50
  • Cause of death: ICD-9 — 3071|3075[ABE]
  • Cause of death: ICD-8 — 30650

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF3
Parent code in ICD-10 F50-F59
Name in latin Perturbationes edendi

Case counts by codes

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FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36341 31953 4251
Only index persons 34663 30911 3752
Unadjusted period prevalence (%)
Whole population 0.82 0.92 0.12
Only index persons 1.03 1.14 0.14
Median age at first event (years)
Whole population 18.09 18.03 18.13
Only index persons 17.90 17.94 17.58

-FinnGen-

Key figures

All Female Male
Number of individuals 3525 3231 294
Unadjusted period prevalence (%) 1.18 1.27 0.15
Median age at first event (years) 22.14 21.32 31.11

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint KRA_PSY_EATING_EXMORE and mortality.

Females

Parameter HR [95% CI] p-value
KRA_PSY_EATING_EXMORE 2.861 [2.39, 3.42] < 0.001
Birth year 0.995 [0.99, 1.0] 0.22

During the follow-up period (1.1.1998 — 31.12.2019), 901 out of 25614 females with KRA_PSY_EATING_EXMORE died.

Males

Parameter HR [95% CI] p-value
KRA_PSY_EATING_EXMORE 3.236 [2.57, 4.08] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 506 out of 3356 males with KRA_PSY_EATING_EXMORE died.

Mortality risk

Mortality risk for people of age

years, who have KRA_PSY_EATING_EXMORE.

N-year risk Females Males
1 0.277% 0.613%
5 1.664% 3.669%
10 4.01% 8.729%
15 7.985% 15.408%
20 13.555% 25.088%

Relationships between endpoints

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Index endpoint: KRA_PSY_EATING_EXMORE – KRA_PSY_EATING

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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