No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
9589 |
4. Check minimum number of eventsNone |
9589 |
5. Include endpointsNone |
9589 |
6. Filter based on genotype QC (FinnGen only) |
9263 |
Control definitions (FinnGen only)
Control exclude
K11_HERNIA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K40-K46
Name in latin
Hernia abdominalis ventralis
Similar endpoints
↥List of similar endpoints to
Ventral hernia
based on the number of shared cases.
Similar with more cases:
- Hernia of abdominal wall
- Hernia
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 78613 | 43855 | 34099 |
| Only index persons | 64802 | 36761 | 28041 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.12 | 1.26 | 0.95 |
| Only index persons | 1.23 | 1.35 | 1.07 |
| Median age at first event (years) | |||
| Whole population | 58.68 | 59.43 | 57.69 |
| Only index persons | 57.46 | 57.95 | 56.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9263 | 5092 | 4171 |
| Unadjusted period prevalence (%) | 2.04 | 2.00 | 2.09 |
| Median age at first event (years) | 57.91 | 56.15 | 60.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_VENTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_VENTHER | 1.349 [1.25, 1.46] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.133 |
During the follow-up period (1.1.1998 — 31.12.2019), 6462 out of 28814 females with K11_VENTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_VENTHER | 1.428 [1.31, 1.55] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 5789 out of 23067 males with K11_VENTHER died.
Mortality risk
Mortality risk for people of age
years, who have K11_VENTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.139% | 0.3% |
| 5 | 0.712% | 1.532% |
| 10 | 1.77% | 3.888% |
| 15 | 3.826% | 7.435% |
| 20 | 6.727% | 12.982% |
Relationships between endpoints
↥Index endpoint: K11_VENTHER – Ventral hernia
GWS hits: 13
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data