≡ Risteys
FG R11 + FR

Documentation Changelog GitHub Contact & Feedback

Vascular disorders of the intestines

DOID EFO Endpoint Browser PheWeb

K11_VASCINT

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K55
  • Hospital discharge: ICD-9 — 557
  • Hospital discharge: ICD-8 — 4442
  • Cause of death: ICD-10 — K55
  • Cause of death: ICD-9 — 557
  • Cause of death: ICD-8 — 4442

2 out of 7 registries used, show all original rules.

2296

4. Check minimum number of events

None

2296

5. Include endpoints

None

2296

6. Filter based on genotype QC (FinnGen only)

2218

Control definitions (FinnGen only)

Control exclude K11_INTESTOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K55-K63
Name in latin Morbositates vasculares intestini

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 23490 12123 11060
Only index persons 16419 8680 7739
Unadjusted period prevalence (%)
Whole population 0.33 0.35 0.31
Only index persons 0.31 0.32 0.30
Median age at first event (years)
Whole population 75.10 77.31 72.72
Only index persons 74.22 76.24 71.95

-FinnGen-

Key figures

All Female Male
Number of individuals 2218 960 1258
Unadjusted period prevalence (%) 0.52 0.38 0.63
Median age at first event (years) 72.01 71.16 72.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Association

Association between endpoint K11_VASCINT and mortality.

Females

Parameter HR [95% CI] p-value
K11_VASCINT 2.045 [1.82, 2.29] < 0.001
Birth year 0.997 [0.99, 1.01] 0.469

During the follow-up period (1.1.1998 — 31.12.2019), 2865 out of 6458 females with K11_VASCINT died.

Males

Parameter HR [95% CI] p-value
K11_VASCINT 2.192 [1.92, 2.51] < 0.001
Birth year 0.987 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 3058 out of 6208 males with K11_VASCINT died.

Mortality risk

Mortality risk for people of age

years, who have K11_VASCINT.

N-year risk Females Males
1 0.205% 0.434%
5 1.305% 2.474%
10 3.229% 6.02%
15 6.079% 10.789%
20 10.404% 18.233%

Relationships between endpoints

↥

Index endpoint: K11_VASCINT – Vascular disorders of the intestines

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data