No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
329 |
4. Check minimum number of eventsNone |
329 |
5. Include endpointsNone |
329 |
6. Filter based on genotype QC (FinnGen only) |
318 |
Control definitions (FinnGen only)
Control exclude
K11_OESSTODUO
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K20-K31
Name in latin
Ulcus pepticum loco non specificato
Similar endpoints
↥List of similar endpoints to
Peptic ulcer
based on the number of shared cases.
Similar with more cases:
- Gastroduodenal ulcer
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4182 | 1927 | 2191 |
| Only index persons | 3048 | 1448 | 1600 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 63.74 | 68.52 | 59.49 |
| Only index persons | 61.57 | 66.17 | 57.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 318 | 150 | 168 |
| Unadjusted period prevalence (%) | 0.07 | 0.06 | 0.08 |
| Median age at first event (years) | 60.01 | 56.13 | 63.48 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint K11_PULC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULC | 1.855 [1.57, 2.19] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.207 |
During the follow-up period (1.1.1998 — 31.12.2019), 586 out of 1363 females with K11_PULC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULC | 2.396 [1.99, 2.88] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 608 out of 1406 males with K11_PULC died.
Mortality risk
Mortality risk for people of age
years, who have K11_PULC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.215% | 0.419% |
| 5 | 1.024% | 2.613% |
| 10 | 2.649% | 6.388% |
| 15 | 4.898% | 11.583% |
| 20 | 8.644% | 19.041% |
Relationships between endpoints
↥Index endpoint: K11_PULC – Peptic ulcer
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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