No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2812 |
4. Check minimum number of eventsNone |
2812 |
5. Include endpoints |
3767 |
6. Filter based on genotype QC (FinnGen only) |
3632 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Diseases of peritoneum
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 39464 | 21229 | 17637 |
| Only index persons | 27099 | 15403 | 11696 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.56 | 0.61 | 0.49 |
| Only index persons | 0.51 | 0.57 | 0.45 |
| Median age at first event (years) | |||
| Whole population | 58.46 | 57.63 | 59.31 |
| Only index persons | 53.19 | 51.22 | 55.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3632 | 1969 | 1663 |
| Unadjusted period prevalence (%) | 0.80 | 0.77 | 0.84 |
| Median age at first event (years) | 52.05 | 46.45 | 58.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_PERITON and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PERITON | 2.786 [2.51, 3.1] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.04 |
During the follow-up period (1.1.1998 — 31.12.2019), 3125 out of 9370 females with K11_PERITON died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PERITON | 3.32 [2.96, 3.72] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 3611 out of 7945 males with K11_PERITON died.
Mortality risk
Mortality risk for people of age
years, who have K11_PERITON.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.243% | 0.629% |
| 5 | 1.55% | 3.252% |
| 10 | 3.803% | 8.169% |
| 15 | 6.69% | 14.447% |
| 20 | 11.757% | 23.741% |
Relationships between endpoints
↥Index endpoint: K11_PERITON – Diseases of peritoneum
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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